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While current treatments focus on symptomatic, palliative, and preventive patient care, future therapeutics should focus on replacement, repair, or compensation of the nonfunctional and/or deficient enzyme through hepatic delivery of the gene or protein

M.Amores-IniestaJ.CompanV.et al (2014)

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MAPK pathway activates CREB transcription factor inducing genes supporting neuronal health and plasticity

While Tesamorelin is not approved for these purposes, it has piqued the curiosity of those seeking potential advantages in body fat reduction and lean muscle mass augmentation

We also identified compound-selective mutations mapping to regions outside of the direct IMiD-binding site