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GLP-1 agonists and tirzepatide achieve 1522% weight loss in clinical trials DSMES (Diabetes Self-Management Education and Support): ADA 2026 Recommendation 5.2 provide DSMES at diagnosis, annually, when complications develop, and at life transitions

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Researchers emphasize the need for larger, well-designed clinical trials to establish safety and effectiveness

Genes involved in tissue repair, collagen synthesis, and antioxidant protection see increased activity, while genes associated with inflammation, tissue breakdown, and cellular aging see reduced expression

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