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In the absence of DM or other cardiac pathologies, the majority of ATP is derived from the oxidation of FAs (60% to 70%), whereas a minor part is derived from the oxidation of glucose, lactate, ketone bodies, and amino acids (20% to 30%), depending on their availability in the blood [20212223]

Part of the images was generated by BioRender ( and GEPIA2 ( We also appreciate the technical support from Core Utilities of Cancer Genomics and Pathobiology of the Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong

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