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Name: foxo4 dri nct FOXO4-DRI improves spermatogenesis in aged mice through reducing senescence-associated secretory phenotype secretion from Leydig cells FOXO4-DRI - Beverly Hills Rejuvenation
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Acknowledgements This work was supported by the grant from the Natural Science Foundation of China (82401786), Natural Science Foundation of Zhejiang Province (LQ24C090002), Qiushi Youth Program from Scientific Research Cultivation Foundation (J-202406), Hangzhou Science and Technology Bureau, Zhejiang Provincial Medical and Health Technology Project (2024KY246), China National Students Research Training Program (202313021031), and the Key Research Project of Joint Institute of Tobacco and Health to MDL (2021JC06)

Since there is bidirectional transport of BDNF through the BBB, we tested the hypothesis that plasma BDNF may be used as biomarker for brain DHA enrichment

Numerous animal studies have demonstrated the effectiveness of this peptide in promoting tissue repair and modulating various biological processes

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These results imply that oligodendrocytes augment BBB integrity via pathways other than those involving platelet-derived growth factor receptor-BB/platelet-derived growth factor receptor signaling exerted by brain endothelial cell-secreted platelet-derived growth factor-BB [98]