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Shown are membrane-bound hemichromes (panel A), complement C3c fragment (panel B) and autologous IgG (panel C) in ring-infected and non-infected GR-deficient RBCs from the index patient, brother (individual 2) and sister (individual 3) of index patient, and from normal GR-sufficient controls

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Moreover, oxidative stress can enhance the expression of adhesion molecules and proteases, facilitating cancer cell detachment, invasion into surrounding tissues, and entry into the bloodstream [120]

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The exception might be intravenous therapies like the MSC case, but even that was experimental

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