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Enzyme autoacylation and acyl-CoA-mediated reversal of calmodulin inhibition of phospholipase A2 activity

The workup should include LH and FSH to distinguish primary from secondary hypogonadism, estradiol to assess aromatization status, SHBG to interpret free testosterone, prolactin to exclude a pituitary adenoma, and a metabolic panel

Additionally, we explore the beneficial and damaging consequences of reactive astrogliosis in dopaminergic neurons during PD, particularly on oxidative damage, which is a main component of numerous neuropathological conditions, and that may have a damaging effect in astrocytic functions