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Apart from getting spicy when applied to skin, LAA is also notoriously unstable as an ingredient, and degrades rapidly in the presence of light and air, making it difficult to keep it shelf-stable in skin care products for extended periods of time

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Injection-Related Complications: If injections aren't performed by a qualified professional using sterile techniques, there's a risk of infection or nerve damage

If an acceptor bead is within 200 nm, energy is transferred from the singlet oxygen to the bead, resulting in light production