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Stem cell therapy for tinnitus aims for symptom reduction and improved quality of life, but it cannot restore dead neurons or completely reverse decades of profound hearing loss

[195] engineered biomimetic DL-loaded PLGA NPs and decorated them with a M2-binding peptide (M2pep)-modified hepatocellular carcinoma (HCC) membrane to prepare DL@NP-M-M2pep NPs (particle size ~ 120 nm) using an extruder

Western blot confirmed comparable TfR1 expression in SH-SY5Y and bEnd.3 cells (Fig

Genes Cells 6, 857868

Numerous damage events The amount of DNA damage that can occur is considerable

Morphologically, ferroptosis mainly manifests as obvious shrinkage of mitochondria with increased membrane density and reduction in or vanishing of mitochondrial cristae, which is a different process from other modes of cell death 1,3,4