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C., Hakansson, N

indicated that in the case of chitosan-stabilized SeNPs the molecular weight of chitosan regulates the Se biological and physicochemical properties, including crystallinity, surface charge density, and hydrophobicity [187]

We propose that chronic exposure to a particular suite of environmental and genetic factors elicits a trajectory of impaired mitochondrial biology that maximally impacts subsets of mitotypes abundant in the substantia nigra, striatum, and cerebral cortex, which eventually surfaces as the hallmark features of PD

Stiripentol, an LDH inhibitor, has been shown to significantly boost the effectiveness of TMZ through a mechanism that involves modulating lactylation [161]