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doi: 10.7150/thno.34065 18 Martin-SanchezDPovedaJFontecha-BarriusoMRuiz-AndresOSanchez-NioMDRuiz-OrtegaMet al

Environmental risk factors of glutathione deficiency include: Exposure to chemical toxins (including pollution) UV radiation exposure Cadmium exposure Chronic stress Excessive alcohol use Smoking Poor diet Certain medications (like Tylenol) Certain illnesses are known to decrease glutathione levels

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The concentration of acrolein relative to the hydrate of 3-HPA was estimated to be less than 5% on the basis of 13 C signal intensity (100 mM 3-HPA, relaxation delay of 30 s)

Mutant huntingtin causes a selective decrease in the expression of synaptic vesicle protein 2C