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For instance, they may reduce your body's sensitivity to insulin and increase your blood sugar

161 In addition, a distinct mechanism was found for a synthetic peptide derived from a keratinocyte-expressed tetraspanin named CD9

Par Health L0H103 Rev 01/2026

In the STEP clinical trials, participants who combined semaglutide with lifestyle interventions lost up to 17.4 percent of baseline body weight, compared to 14.9 percent for those with less intensive behavioral support