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The primary endpoints that track response to MOTS-c therapy align with the peptide's core mechanisms: insulin sensitivity, mitochondrial function, body composition, and inflammatory tone

J Vet Med Sci 2016;78:957-62.ArticlePubMedPMC 73

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Research in rats shows that the peptide substantially increases the rate of collateral blood vessel growth in the setting of ischemia [4]

DSIP improves sleep quality via stress-hormone regulation

MATERIALS AND METHODS Animals and experimental design Animals were provided access to regular chow and water ad libitum and were maintained at a temperature of 212 and humidity of 6010% on 12-h light/dark cycles