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Fjalldal S, Follin C, Gabery S, Sundgren PC, Bjorkman-Burtscher IM, Latt J, et al

Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis

Steroids, diphenhydramine and bronchodilators can help resolve the anaphylactoid reactions and should be given so that NAC therapy can be continued under close monitoring.72 The oral formulation has a sulfur component, and thus has an unpleasant taste and smell that can cause nausea and vomiting

It converts it back to its active, reduced form (GSH)

This effect can protect healthy tissues from oxidative damage and contributes to chemoprevention (153)

They were maintained under a 12 h light-dark cycle (lights on from 8:00 AM to 6:00 PM) at a temperature conducive to mouse survival (2325 C) and 50% humidity, with ad libitum access to water and food