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In addition, chitosan nanocarriers can directly deliver drugs to the lymphatic system through lymphatic targeting technology, increase local drug concentration and reduce systemic toxicity

V., & Bobyreva, S

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doi: 10.1016/S0014-2999(97)01033-9

1993/02/01/1993;53(2):222-229.doi: Tavoni A, Vitali C, Bombardieri S, Pasero G

However, a unique feature that may help mitigate the potential placebo effects is that the treatment benefits typically wear off 12 weeks prior to the next scheduled injection, and the benefits are reinstated following each injection