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In: M.E

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Animals and experimental design The study was approved by the Marmara University School of Medicine Animal Care and Use Committee (Protocol Number: 55.2021.mar)

First, its interplay with lipid metabolism: surplus pyruvate generated through glycolysis is converted to acetyl-CoA, which can enter lipid biosynthetic pathways and promote the synthesis of fatty acids, particularly PUFAs

For hypoxic experiments, cells were exposed to normoxia (21% O 2 ) and moderate hypoxia (0.2% O 2 ) for 48 h using a modular atmosphere-controlled system Whitley H85 hypoxystation- Don Whitley Scientific

However, the rate of wild-type MTHFR 677 in patients with venous thromboembolism was the same as that compared to the control healthy patients (6)