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The research rationale for a selective NNMT inhibitor is to interrupt exactly that diversion, so the cell keeps more of its NAD+ pool and can run its mitochondrial machinery again

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Additionally it was noted that in the rats treated with AOD9604, there were increased rates of lipolytic activity, as well as no negative effect on insulin sensitivity which has been seen in animals treated with human growth hormone ( A similar study conducted by Heffernan et