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Another critical component, alternative oxidase (AOX), attenuates mitochondrial ROS generation by providing an alternative electron transport route within the respiratory chain

Visualization of biodistribution and deep tumor penetration Cy5-labeled paclitaxome (70 mg PTX kg 1 ) or Cy5/PTX/LipoSM (40 mg PTX kg 1 ) were intravenously injected into orthotopic 4T1-Luc2 or KPC-Luc tumors mice ( n = 3 mice/group, ~400 mg)