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Metastasis-on-a-chip mimicking the progression of kidney cancer in the liver for predicting treatment efficacy

Experiments with colorectal tumors in mice revealed that SLC7A5 deletion significantly reduced the number of tumors in the small intestine and colon, suggesting that SLC7A5 promotes tumor occurrence and development [42]

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This strategy of alternating treatments between each subsequent animal or cage was used to minimise the likelihood of confounding effects

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