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Semaglutide has become very popular because clinical studies show it can lead to about 15% body weight loss on average

Awosemo, O., et al

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These figures are not extrapolated from a human trial (there isnt one) and they are not scaled from the mouse papers

I also requested a medical necessity letter and had it in my inbox by the next morning

When NNMT is overactive, it consumes excess NAD+, leaving less available for these critical processes