In solvent -80C, 6 months , -20C, 1 month All Endogenous Metabolite Isoforms More Biological Activity [1]
This movement of Ca 2+ ions is closely coupled with the oxidative phosphorylation that generates the negative mitochondrial membrane potential (MMP) and allows ATP production by the F 1 F 0 -ATPase

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However, it is crucial to mention that the overall scientific evidence remains inconsistent