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For instance, GPX4 inhibitors have shown efficacy in targeting persister cancer cells [104]

Zinc finger protein 143 (ZNF143) and lncRNA NEAT1 were upregulated in FFA-treated hepatocytes

A study published in the Journal of Pineal Research documented the decline in pineal melatonin production in relation to Alzheimer disease progression

7.2 Targeting enzymes involved in de novo FAS Since the role of FASN is important in supporting both anabolic metabolism and oncogenic signaling, targeting FASN for cancer therapy might be promising

Mitochondrial damage Mitochondria act as pathological triggers, mediators, and effectors of hepatic IRI [6]

Therefore, it is important to test the predictive value of the GSTM1 -null variant before population-based association studies are conducted