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Although administration of this ester appeared safe and had protective properties in this model, it also is not commercially available at this time

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Deficiency can lead to the faulty or insufficient production of lipids, from which myelin is composed (25, 26)

Specifically, -hydroxybutyrate can effectively inhibit the activation of the NLRP3 inflammasome, and preclinical studies have demonstrated its ability to reduce BBB permeability (133)

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These pieces of evidence strongly complement our above discussion on the crosstalk of Nrf2 and NF-B in drug-induced hepatotoxicity, demonstrating that this connection may provide an insight into the development of future hepatoprotective agents