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Furthermore, multiple studies have confirmed that aggravated inflammation and accelerated glycolysis are tightly implicated in RA

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It attenuates lipid deposition present in the kidney by activating AMPK phosphorylation, which upregulates insulin-induced gene 1 (Insig-1) expression in PA-induced renal tubular epithelial cell lines(NRK-52E) and delays DKD (195)