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Notably, alcohol-associated iron overload promotes the proliferation of pathogenic and opportunistic gut bacteria, while dysbiotic microbiota further disrupt iron homeostasis through metabolite-mediated regulation, creating a vicious cycle that perpetuates oxidative stress and ferroptosis

Endothelial cells express adhesion molecules such as VCAM-1 and ICAM-1, leading to endothelial inflammation

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Researchers analysed data from England, Scotland, the US, Nordic countries, Australia and Japan

To overcome these constraints, surface-directed conjugation strategies have emerged as a promising alternative