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High concentrations of ascorbic acid can destabilize copper peptides, reducing their effectiveness

Morning intake can help combat oxidative stress throughout the day, while evening intake supports detoxification during sleep

PubMed Central , Pharmacology & Therapeutics , vol

On the other hand, in rice noe1 mutant, in the absence of OsNOE1/OsCATC function, the accumulation of H 2 O 2 induces NO production through elevating nitrate reductase expression, which is further integral to H 2 O 2 induced leaf cell death through S -nitrosylation of GAPDH and thioredoxin (Wang et al., 2013)

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