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Metabolic enzymes and transporters often co-regulate drug elimination, sharing substrates and tissue distribution

However, owing to the high false-positive rates of cytology, colposcopy with directed biopsy is often required for further evaluation

There is no well-documented evidence from the literature, however, of true allergic or idiosyncratic reactions to thyroid hormone

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Conversely, since GC excess stimulates hypothalamic AMPK (driving increased appetite) and hepatic AMPK activity (contributing to fatty liver), adrenal insufficiency should result in AMPK inhibition at these sites