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Another reading suggests that broad gene-expression effects can reflect secondary consequences (changes in cell state, in proliferation rate, in metabolism) rather than direct mechanism-based effects, and that the specificity of the transcriptomic findings should be interpreted with caution

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David's Medical Center, Austin, United States, 4 Trident Medical Center, Charleston, United States, 5 HCA Midwest, Overland Park, United States, 6 Medtronic, Minneapolis, United States Background and Aims: Phase I of the DiVERT study revealed heterogeneities and deficiencies in post-stroke cardiac monitoring among institutions

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Notably, gemcitabine was not used in this setting, because our preliminary studies had demonstrated that extended exposure to gemcitabine in the 3D setting resulted in a complete loss of cancer cells on the top of the matrices