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It can actually travel to the hippocampus, and at least in these animal studies, induce the proliferation of neurons, growth of synapses, BDNF, a number of downstream things, which kind of makes sense if we were to put a just-so evolutionary story on this

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[] Moreover, the ethyl acetate extract of fermented noni fruit contains quercetin as a key constituent responsible for its anti-inflammatory activities, while additional unidentified compounds further enhanced quercetins inhibition of COX-2 expression

Fernndez-Rhodes L, Howard AG, Tao R, Young KL, Graff M, Aiello AE, North KE, Justice AE (2018) Characterization of the contribution of shared environmental and genetic factors to metabolic syndrome methylation heritability and familial correlations

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