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doi: 10.1016/j.molmed.2022.02.003 12 TuHZhouYJTangLJXiongXMZhangXJAli SheikhMSet al

Using individual variation in GSH combined with a repeated measures approach is a highly effective form of randomization

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however, there were important limitations to consider, including small sample sizes, a lack of long-term observation, the use of a single species or strain, the lack of in-depth exploration of cellular or molecular mechanisms, failure to assess other aspects of reproductive function, a lack of validation of the clinical relevance, and a failure to consider individual differences in drug dosages

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