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The safety profile of the combined therapy was similar to the safety of monotherapies (104)

Our complementary UV-vis and fluorescence anisotropy spectroscopic analysis, together with molecular modeling, shows that the combination of the three studied mutations removes critical structural constraints at key microdomains, allowing the formation of an active-like conformation in the dark

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For detection, the following wavelengths were usable: 340, 380, 412, 450, 505, 546, 570, 605, 660, 700, 740 and 800 nm

Results: The review reveals that plant extracts with neuroprotective properties exert anti-PD effects through mechanisms including antioxidant and anti-inflammatory actions, inhibition of -synuclein (-syn) aggregation, enhancement of dopaminergic neuron survival, and restoration of synaptic function