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This correction is important because of the relatively small volumes of distribution of these water-soluble drugs

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B12 is essential for nerve function, red blood cell production, and brain health, and even a single heavy session of nitrous oxide use can trigger a cascade of neurological damage that includes tingling, numbness, muscle weakness, and in severe cases irreversible spinal cord injury

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It activates antioxidant enzymes such as superoxide dismutase (SOD), promotes collagen and elastin synthesis, and suppresses fibrotic pathways by inhibiting TGF-?1 signaling

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