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NAC and its antioxidant properties NAC appears to support the synthesis of glutathione (GSH) under conditions when the demand for GSH is increased, during oxidative stress

Pathol Res Pract2025 Sep 29:275:156253

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Additionally, KD activates peroxisome proliferator-activated receptor , which suppresses NF-B expression and mitigates neuronal damage associated with N-methyl-D-aspartate (NMDA) excitotoxicity [57, 58]

Cell death within this anatomical region was quantified via manual (blind) counting of the total number of Fluoro-Jade C positive fluorescent neurons within at least two fields of interest per section