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As, if the vitamin B 12 levels are high, the causes for it are severe warranting management

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Clinical Manifestations of Vitamin B12 Deficiency Although the classic hematologic expression of vitamin B 12 deficiency is a megaloblastic macrocytic anemia characterized by an elevated mean corpuscular volume and mean corpuscular hemoglobin, and a peripheral smear containing macroovalocytes and hypersegmented neutrophils, up to 28 percent of affected patients may have a normal hemoglobin level, and up to 17 percent may have a normal mean corpuscular volume

The metE protein was formulated in two distinct adjuvants, AddaS03 and AS01, capable of inducing robust immune responses with a high safety profile ( MTB and lungs and spleens were collected for bacterial enumeration at the end of the study ( Figure 5A )

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