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One such factor is reduced retinal blood flow, which exacerbates ischemia, causing the accumulation of glutamate and other neurotoxic substances and creating a hypoxic environment in the retina (112)

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Hemolytic anemia due to hemolysis has been observed in some patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency after receiving large IV or oral doses of ascorbic acid

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