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Polymeric nanoparticles, such as those generated from polylactic-co-glycolic acid (PLGA) or polyethylenimine (PEI), also appear promising, as these materials can be tailored to deliver siRNA precisely to microglia or neurons while allowing for prolonged release (96)

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Nat Rev Cardiol 16(3):137154 Thabet E, Dief AE, Arafa SA-F, Yakout D, Ali MA (2024) Antibiotic-induced gut microbe dysbiosis alters neurobehavior in mice through modulation of BDNF and gut integrity