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Results CTIF is localized in the aggresomes Our previous report revealed that endogenous CTIF is localized to the cytoplasmic side of the perinuclear region, supporting our model that CTIF is loaded onto the 5-end of newly synthesized mRNAs that are being exported from the nucleus to the cytoplasm through the nuclear pore complex 6

NAC, which increases glutathione levels in the brain, improved symptoms of schizophrenia in clinical studies [22]

10.1038/ncb3255 91

Anti-BP230 IgE autoantibodies in bullous pemphigoid intraindividually correlate with disease activity

Semaglutide activates GLP-1 receptors in the brain that regulate hunger signals

48,49 This GSH depletion impairs the capacity of GPx4 to reduce lipid hydroperoxides and to interrupt the propagation of LPO