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The synthetic NBD peptide, which mimics the S100A4-binding domain of MetAP2, has been demonstrated to regulate the expression of genes related to angiogenesis and suppress capillary formation in murine endothelial cells (Takenaga et al., 2021)

& Constancia, M

Emerging evidence has suggested that mitochondrial dysfunction and ferroptosis are not uniformly engaged across the course of IDD but instead display stage-dependent features (32,33)

The compound is a stable partial sequence of the native 98-residue parent protein and has been shown to exhibit stability in both acidic gastric environments and physiological pH conditions

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