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Protein availability : Conditions like pernicious anemia can reduce or eliminate protein production

The median body weight at the time of switch was 85.7 kg

In both methionine-choline-deficient (MCD) diet-fed mice and palmitic acid (PA)-treated hepatocytes, GADD45 deficiency exacerbated lipid accumulation and upregulated lipogenic genes (SREBP1, FASN, ACC)