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Differences in protein profiles of kefir grains from different origins when subcultured in goat Milk

doi: 10.1038/s41586-019-1405-y 88

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This interaction between bile acids and TGR5 reduces NLRP3 inflammasome activation, inhibits NF-B signaling, and induces IL-10 production via CREB [208]

In addition, oxidative stress leads to the activation of the NF-B signaling pathway and the synthesis of proinflammatory cytokines, thus ROS production by CYP4A11 metabolism of FFA relates to inflammatory reactions (Gao et al