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& Miyadera, T

For example, free heme triggers macrophage Toll like receptor 4 (TLR4) activation and TNF- production, as well as ROS-mediated NLRP3 inflammasome induction (7779) via binding by macrophage Fc and lectin-like receptors (80), and that such parasites may be more susceptible to ROS (81)

For cell treatment by APAP precursors, HepaRG cells and primary human hepatocytes were first incubated with 50 g/ml of APAP or APAP-cys in the maintenance medium described above, during 0.5 h, 2 h, 6 h, 24 h, or 48 h, to optimize the incubation time required to detect APAP metabolites

10.3390/ijms19092549 21 BrodinH

Coppock, D., Kopman, C., Gudas, J

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