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To determine whether the colistin-induced depolarization was the result of the opening of the mitochondrial permeability transition pore (mPTP), mitochondria were co-incubated with colistin and cyclosporin A, a well-characterized desensitizer of the mPTP 31,32

10.1371/journal.pone.0032388 60 GongG.SongM.CsordasG.KellyD

For instance, metformin can activate SIRT1 and regulate related pathways to mitigate LPS-induced SAKI and improve renal function of HFD-/STZ-induced diabetic rats (Xu et al., 2020

Autism Res (2009) 2:98108.10.1002/aur.70 79 MohammadNSJainJMChintakindiKPSinghRPNaikUAkellaRR

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