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Stage matters: choosing relevant model systems to address hypotheses in diet and cancer chemoprevention research

The yields of these over-expressed recombinant proteins dropped considerably due to IB formation, indicating aggregation

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[DOI] [PMC free article] [PubMed] [Google Scholar] Sumida T

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In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]