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Labwork at that time was notable for an elevated uric acid of 10.6mg/dl (reference range: 3.5 - 8.5 mg/dl.) Out of concern for TLS precipitating hyperuricemia in the setting of a high-grade tumor in addition to starting a new chemotherapy regimen, the patient was additionally given 10mg of rasburicase and started on 300mg of allopurinol daily

Medicine 95 , e5254 (2016)

Discussion The efficacy and safety of therapeutic agents are significantly influenced by individual patient variations, disease complexity, and drug metabolism

38 This can induce further recruitment of Th17 cells and neutrophils, producing a pathological vicious cycle

Sebastian M, et al

Mit zunehmendem Alter und unter dem Einfluss von Stress , unzureichender Ernhrung und Umweltfaktoren sinkt der Glutathionspiegel im Krper, daher ist es sinnvoll, fr ausreichende Zufuhr durch Nahrungsergnzungsmittel zu sorgen