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Consequently, AMP inhibitors or glucose supplementation can be utilized to promote ferroptosis [95, 96]

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A recent study further demonstrated that proline catabolism via PRODH supports 3D growth of breast cancer cells, with elevated PRODH expression and proline oxidation in metastatic lesions compared with primary tumors, thereby promoting metastatic colonization and identifying PRODH as a potential target for metastasis suppression 64

J Plant Physiol 162:291299 nyayar S, Kele Y, eki F (2005) The antioxidative response of two tomato species with different drought tolerances as a result of drought and cadmium stress combinations