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Twelve weeks of sulforaphane supplementation to children with ASD and related neurodevelopmental disorders significantly improved ABC and SRS scale scores, and urinary metabolites (amino acid/gut microbiome, neurotransmitters, oxidative stress, sphingomyelin and hormones) related to changes in symptoms can be used to determine pathways playing an role in action mechanism of interventions aimed at alleviate ASD symptoms [120]

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