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In antioxidant defence, glutathione is very important because it helps cells deal with oxidative stress and keep their internal environment stable

Antimicrob Agents Chemother 50(6):20792086 Holazo AA, Winkler MB, Patel IH (1988) Effects of age, gender and oral contraceptives on intramuscular midazolam pharmacokinetics

Thus, ascorbate reductases like MDHARs, which are responsible for the reduction of AsA have considerable roles in stress tolerance

Nuclear factor erythroid 2-related factor 2 (Nrf2) is one of the key transcription factors regulating antioxidant system activity

It remains unclear whether distinct death signals are activated sequentially, in parallel, or undergo context-dependent modulation at the single-cell or population level-particularly across different respiratory epithelial subtypes and immune cell populations under diverse stress conditions

In the current study, APAP reduced the diversity of intestinal flora in mice, which was reduced through GC treatment, and hence, the liver restored its physiology upon application of GC