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10.16943/ptinsa/2014/v80i1/55089 4

In a high-oxidative-stress environment rich in superoxide, NO is rapidly converted to pro-ferroptotic ONOO

Avoid layering with strong acids or retinoids initially

These reactions become a significant source of OH in the presence of oxidative stress conditions or when the concentration of free, unbounded transient ions rises, as in the case of hemodialysis