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10.1038/s41598-018-26704-x [DOI] [PMC free article] [PubMed] [Google Scholar] Koike H., Ishida A., Hayashi T., Shimamura M., Mizuno S., Nakamura T., et al

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In adults, treatment length varies based on symptom relief and IGF-1 targets, and some may use it indefinitely if benefits persist (with periodic re-evaluation)