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TTC5 has previously been shown to downregulate ATP synthase activity, which sensitizes cells to mitochondrial-dependent apoptosis via enhanced p53 activity (72)

Thioltransferase in human red blood cells: kinetics and equilibrium

p = 0.054)

An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site

Benefits Disrupts the survival network of senescent cells: Senescent cells enter a state of permanent growth arrest but resist apoptosis despite accumulating DNA damage and oxidative stress