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It has been shown to upregulate the expression of genes involved in lipid clearance while activating AMP-activated protein kinase (AMPK) and downregulating sterol regulatory element-binding protein 1c (SREBP-1c), a transcription factor central to hepatic lipogenesis

It has also been associated with other auto-immune disorders like diabetes mellitus and thyroid disease

In the next sections, we review what we have learnt about the effects of UV light on lens transparency from a variety of different animal models and critically assess whether these models accurately model the effects of UV exposure seen in the human lens

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So does the supplementation requirement

10.1016/j.biocel.2013.05.016 58